Thanks for the wonderful and information-rich seminar earlier this month, Kandace. A few questions I had from the seminar:
You mentioned in your talk that insulin overstimulates the ovarian thecal cells, which in turn up-secrete androgens... And it also causes aromatase to convert these androgens peripherally (rather than centrally) to estrogen, leading to estrogen dominance. Do you often observe estrogen dominance as a co-morbidity with PCOS and/or IR? What are common things to look for? Are there also different phenotypes?
Also, do you have any online or book resources for better understanding the endocrinology and immunology of IR and inflammation? (E.g., insulin's effects on HPO axis, etc., as with my question above.) Similarly, do you have any recommended resources for interpreting BBT charts, beyond the "sawtooth" look you've observed in liver qi stagnant PCOS patients? In fact, any "further reading" recommendations would be great!
Thanks again for sharing your extensive understanding of this aspect of women's health. :)